Collections
NEWS - Timely articles written from a journalistic perspective on hot areas in the bone field.
Multifactorial Interventions to Prevent Falls: Is There Reason to Doubt Their Effectiveness?
Neil A. Andrews
Do multifactorial interventions actually prevent falls? While a recent meta-analysis casts some doubt on the usefulness of falls interventions, falls prevention experts remain optimistic for the future of these programs.
[Full Text] [PDF]
PERSPECTIVES - Insightful, thematic reviews of key topics on both the basic science and clinical sides.
Bone Cells, Osteoprogenitors, and Hematopoiesis
Paolo Bianco
Which cells establish and maintain the hematopoietic stem cell niche? Do skeletal stem cells and hematopoietic stem cells interact with each other? Can hematopoiesis occur in the absence of bone? These are among the many intriguing questions Dr. Bianco addresses in his review.
[Abstract] [Full Text] [PDF]
COMMENTARIES - Analyses of specific pathbreaking papers appearing in all of the major scientific and medical journals.
A New PPAR-γ Function in Bone
By Ichiro Takada and Shigeaki Kato
A recent Nature Medicine paper, reporting results from PPAR-γ knockout mice, suggests a new role for PPAR-γ in osteoclastogenesis. The authors discuss the new research and its implications for osteoporosis treatment. Could PPAR-γ antagonists or selective PPAR-γ modulators one day be used as osteoporosis therapies?
[Full Text] [PDF]
MEETING REPORTS - Comprehensive examinations of new findings presented at the major bone meetings.
Cancer Stem Cells and Bone, and Cancer Cell Dormancy and Bone Metastasis: Meeting Report from Skeletal Complications of Malignancy V
Gordon J. Strewler
[Full Text] [PDF]
NOT TO BE MISSED - Annotations, written by the IBMS BoneKEy® editors, on the most important articles published in the literature each month.
Bolland et al. Effects of intravenous zoledronate on bone turnover and BMD persist for at least 24 months. J Bone Miner Res. 2008 Aug;23(8):1304-8.
Thirty-three HIV-infected men completed a randomized trial of 4 mg annual zoledronate or placebo and were studied for 12 months off treatment. Turnover markers remained suppressed and...
[Full Text] [PDF]
ARTICLES - Unique content covering special topics, such as new clinical guidelines.
The National Osteoporosis Foundation Clinician's Guide to Prevention and Treatment of Osteoporosis, 2008: A New Guidance to Establish a Standard of Care for Prevention of Osteoporosis-Related Fractures
Ethel S. Siris
[Full Text] [PDF]
ELECTRONIC LETTERS TO THE EDITOR - Comments submitted by readers in response to original content published on BoneKEy.
Predicting Fracture Risk: Easily Misled
John A. Kanis, Anders Oden, Helena Johansson and Eugene V. McCloskey
[Full Text]
